PRO/EDR> Buruli ulcer - Sao Tome and Principe (03): A. fumigatus, PCR, bone biopsy, RFI

Aspergillosis -- Sao Tome & Principe
In March 2016 we started following a patient from Sao Tome with severe leg ulcer, complicated with bacterial infection and extension to bone. In December 2016, an _Aspergillus fumigatus_ DNA was found in a bone biopsy.
The patient has improved since, with anti-fungal therapy (first with itraconazole and in the last 2 months changed to voriconazole). I think this is a possible etiology.
It was a very difficult diagnosis, because normal fungal cultures were negative. We also did DNA and

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