Thursday 31 December 2020

PRO/AH/EDR> Plague - Congo DR (12): (IT)

Plague -- DR Congo
Between 15 Nov 2020 and 13 Dec 2020, the Biringi health zone, located in the territory of Aru, Ituri province, DR Congo, reported 151 suspected cases of bubonic plague with 5 deaths (case fatality rate [CFR] 3.3%).
On 22 Nov 2020, the head nurse of the Kumbuku health center (trained in plague outbreak investigation while working in Aru health zone) diagnosed plague in an 11 year old boy brought in as an emergency to the health center by his family in an altered general status (coma, high

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PRO/AH/EDR> COVID-19 update (562): viral load, UK vacc dose, ECDC, WHO

COVID-19 -- United Kingdom
Viruses constantly change through mutation, and so the emergence of new variants is an expected occurrence and not in itself a cause for concern; SARS-CoV-2 is no exception. A diversification of SARS-CoV-2 due to evolution and adaptation processes has been observed globally.
While most emerging mutations will not have a significant impact on the spread of the virus, some mutations or combinations of mutations may provide the virus with a selective advantage, such as increased

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PRO/AH> Bluetongue - Europe (14): Montenegro (DA) cattle, st 4, OIE

Bluetongue -- Montenegro
Information received on [and dated] 28 Dec 2020 from Ms Vesna Dakovic, acting director, Administration for Food Safety, Veterinary and Phytosanitary Affairs, Ministry of Agriculture and Rural Development, Podgorica, Montenegro
Summary
Report type: immediate notification
Date of start of the event: 17 Dec 2020
Date of confirmation of the event: 21 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 22 Jan 2018
Manifestation of disease:

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PRO/AH/EDR> Yellow fever - Africa (26): Nigeria, Senegal, WHO

Yellow Fever -- Nigeria
The Nigeria Centre for Disease Control (NCDC) reports one additional confirmed yellow fever [YF] case the week ending 25 Dec [2020] in Delta state. NCDC is currently responding to reports of yellow fever cases in 13 states: Akwa Ibom, Bauchi, Benue, Borno, Delta, Ebonyi, Enugu, Gombe, Kogi, Osun, Oyo, Plateau, and Taraba states.
Since the summer [2020], Nigeria has reported 102 confirmed yellow fever cases, including 17 deaths (case fatality rate [CFR] 15.5%). The deaths were reported among

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Wednesday 30 December 2020

PRO/AH/EDR> Undiagnosed deaths, poultry - India: (KL) duck, RFI

Undiagnosed -- India
With ducks dying in large numbers in Kuttanad and upper Kuttanad, samples of affected birds will be sent to the National Institute of High-Security Animal Diseases (NIHSAD), Bhopal, for analysis. According to authorities, around 22 000 ducks died in the past week or so. The majority of the dead ducks belonged to 2 farmers in Thalavady and Pallippad grama panchayats.
The decision to send samples to NIHSAD was taken after tests conducted at a virology lab in Thiruvananthapuram [were]

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PRO/AH/EDR> Rhinotracheitis, bovine (IBR/IPV) - Switzerland (02): (GR) cattle, OIE

Other Animal Disease -- Switzerland
Information received on [and dated] 22 Dec 2020 from Mr Hans Wyss, chief veterinary officer, Schwarzenburgstrasse 161, Swiss Federal Veterinary Office, Liebefeld-Berne, Switzerland
Summary
Report type: immediate notification
Date of start of the event: 9 Dec 2020
Date of confirmation of the event: 18 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: May 2015
Manifestation of disease: clinical disease
Causal agent: bovine herpesvirus

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PRO/AH> Crayfish plague - Italy: (FV) European freshwater crayfish, OIE

Other Animal Disease -- Italy
Information received on [and dated] 28 Dec 2020 from Dr Davide Lecchini, chief veterinary officer, Directorate General for Veterinary Health and Veterinary Medicinal Products (DGSAF), Ministry of Health, Rome, Italy
Summary
Report type: immediate notification
Date of start of the event: 20 Nov 2020
Date of confirmation of the event: 15 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 2 Sep 2020
Manifestation of disease: clinical

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PRO/AH/EDR> Fowl typhoid - Honduras (02): (CM) poultry, OIE

Other Animal Disease -- Honduras
Information received on [and dated] 27 Dec 2020 from Dr Rafael Enrique Rodriguez Alvarado, [head of the Animal Health Epidemiology Department, Animal Health Technical Sub directorate, National Service for Agriculture and Livestock (SENASA), Ministry of Agriculture and Livestock], Tegucigalpa, Honduras
Summary
Report type: immediate notification
Date of start of the event: 2 Dec 2020
Date of confirmation of the event: 10 Dec 2020
Reason for notification: reoccurrence of a listed

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PRO/AH/EDR> COVID-19 update (561): variants, China serosurvey, psychosis, WHO

COVID-19 -- China
Authors:
Jamil N Kanji (1), Kanti Pabbaraju (1), Matthew Croxen (1), Sandy Shokoples (1) Anita A Wong (1), Kara Gill (1), Vincent Li (1), Nathan Zelyas (1), Brent Friesen (2,4), Robert Verity (3), Mathew Estey (3), Christopher Sikora (4), Nicholas Etches (4), Deena Hinshaw (2), Graham Tipples (1).
Affiliations:
1. Public Health Laboratory, Alberta Precision Laboratories, Alberta, Canada; 2. Office of the Chief Medical Officer of Health, Alberta Health; 3. DynaLIFE Medical Labs; 4. Public

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PRO/AH> Strangles - North America (06): USA (MA) horse

Strangles -- United States
Horses in 2 Massachusetts counties have tested positive for strangles since the beginning of this month [Dec 2020], according to The Equine Disease Communication Center (EDCC). The 1st case was confirmed on 14 Dec 2020 in Bristol County. The horse was kept at a public boarding facility where 10 other horses were potentially exposed. The EDCC reports no other cases among those horses. The 2nd case was in a horse at a private facility in Plymouth County. There is no report of other horses

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PRO/AH/EDR> Tetrodotoxin poisoning, puffer fish - Philippines

Food-related toxin -- Philippines
Three residents in Tabango, Leyte have died due to food poisoning after eating puffer fish, locally known as "butete". The victims are residents of Sitio Patay, Brgy. Tabing, Tabango, according to a report from the Tabango Municipal Police Station. Four other individuals they ate with were also hospitalized with food poisoning.
Initial police investigation showed one of those who died cooked puffer fish on Monday [28 Dec 2020] and offered it for free to customers of his barbeque stand

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PRO/AH> Ehrlichiosis - Australia (05): (WA) dog

Other Animal Disease -- Australia


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PRO/AH> Equine influenza - Canada: (AB) horse

Equine Influenza -- Canada
An attending veterinarian has confirmed 2 equids at a boarding facility in Strathcona County, Alberta, Canada with equine influenza. Twelve additional horses at the facility were exposed.
The affected equids include a 4 year old Welsh-cross mare and a 5 year old Welsh-cross gelding. The gelding began coughing on 12 Dec 2020, and the mare showed signs of nasal discharge the next day. Both horses were confirmed positive on 16 Dec 2020. Neither horse was vaccinated. A voluntary quarantine was

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Tuesday 29 December 2020

PRO/AH/EDR> Avian influenza (120): Ukraine (KV) poultry, HPAI H5, OIE

Avian Influenza -- Ukraine
Information received on [and dated] 24 Dec 2020 from Dr Olga Shevchenko, deputy head, State Service of Ukraine on Food Safety and Consumer Protection, Ministry of Agrarian Policy and Food of Ukraine, Kyiv, Ukraine
Summary
Report type: immediate notification
Date of start of the event: 23 Dec 2020
Date of confirmation of the event: 24 Dec 2020
Reason for notification: 1st occurrence of a listed disease
Manifestation of disease: clinical disease
Causal agent: highly pathogenic avian

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PRO/AH/EDR> Undiagnosed die-off, avian - USA (02): (ID) duck, aspergillosis

Aspergillosis -- United States
Response from the USGS National Wildlife Health Center:
3 mallard ducks (_Anas platyrhynchos_) collected by the Idaho Department of Fish and Game (IDFG) from this mortality event were necropsied at the US Geological Survey's National Wildlife Health Center in Madison, Wisconsin, USA. Gross and microscopic lesions in the lungs were consistent with acute aspergillosis. Additionally, _Aspergillus fumigatus_ was confirmed on fungal culture of the lung.
We have thus determined the cause of this

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PRO> Invasive mosquito - Dominican Republic

Pests -- Dominican Republic
Abstract
--------
_Aedes vittatus_ Bigot is distributed throughout Africa, tropical Asia, and southern Europe and occurs in sylvatic as well as peridomestic environments where it readily feeds on humans. Although the vectorial capacity of _Ae. vittatus_ is not well understood, this species is known to play a role in the maintenance and transmission of yellow fever, Zika, chikungunya, and dengue viruses within its native range. In October 2019, after a routine inspection of mosquito-breeding

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PRO/AH/EDR> COVID-19 update (560): variants, Thailand, viral shedding, WHO

COVID-19 -- South Korea
Detection of replication-competent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most reliable indicator of contagiousness. [1] Although the duration of live-virus shedding is well-characterized in immunocompetent patients with coronavirus disease 19 (COVID-19), little is known about how long immunocompromised patients are contagious. Consequently, the Centers for Disease Control and Prevention (CDC) guidelines on transmission-based precautions for immunocompromised

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PRO/EDR> Poliomyelitis update (24): global (WPV1; cVDPV2)

Polio -- Pakistan
New wild poliovirus isolates reported this week:
Acute flaccid paralysis (AFP) cases: 1
Environment: 2
Others: 0
New circulating vaccine-derived poliovirus (cVDPV) isolates reported this week:
AFP cases: 29
Environment: 25
Others: 5
Headlines
- The 19th report of the Independent Monitoring Board (IMB) has been published. The IMB notes the strong resumption of polio campaigns following the temporary pause due to COVID-19 and commends the programme for supporting COVID-19 response

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PRO/AH/EDR> Avian influenza (119): Germany (SN) poultry, HPAI H5N8, OIE

Avian Influenza H5N8 -- Germany
Information received on [and dated] 25 Dec 2020 from Dr Dietrich Rassow, director for animal health and animal welfare, chief veterinary officer, Directorate of Animal Health and Animal Welfare, Federal Ministry of Food and Agriculture, Berlin, Germany
Summary
Report type: immediate notification
Date of start of the event: 24 Dec 2020
Date of confirmation of the event: 25 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 1 Feb

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Monday 28 December 2020

PRO/AH/EDR> Leishmaniasis - Syria: (DY) cutaneous

Leishmaniasis -- Syria
Officials at Hajin Hospital are reporting a widespread surge of cutaneous leishmaniasis, aka Aleppo boil, among children in Hajin and its villages east of Deir ez-Zor, according a Radio Al-kul report. It is reported that 1750 cases among children have been seen this year [2020] in the area and demonstrates the need for urgent medical intervention.
Leishmaniasis lesions require lengthy and expensive treatment because the medication is imported. It is difficult for the people to treat

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PRO/AH/EDR> COVID-19 update (559): immunity duration, South Asia, stillbirths, WHO, global

COVID-19 -- Afghanistan
Abstract
--------
Waning humoral immunity in coronavirus disease patients has raised concern over usefulness of serologic testing. We investigated antibody responses of 58 persons 8 months after asymptomatic or mildly symptomatic infection with severe acute respiratory syndrome coronavirus 2. For 3 of 4 immunoassays used, seropositivity rates were high (69.0%-91.4%).
--
communicated by:
ProMED-mail

[Selection criteria for this study were PCR confirmed cases in individuals in

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PRO/AH/EDR> Undiagnosed deaths, buffalo - Taiwan (02): (Yangmingshan N Park) malnutrition susp

Undiagnosed -- China
The initial findings of an investigation into the recent deaths of 25 wild water buffaloes in Yangmingshan National Park in Taipei indicate that the animals were victims of malnutrition, the spokesman for the park headquarters said on Monday [21 Dec 2020].
At a meeting of experts held by the Taipei City Animal Protection Office earlier in the day to discuss the issue, contagious diseases, pesticides, and fences on the mountains were ruled out as causes of death. A "composite environmental

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Sunday 27 December 2020

PRO/AH/EDR> Yellow fever - Americas (14): Brazil (PR) monkeys

Yellow Fever -- Brazil
In a follow-up report on the yellow fever situation in Parana state, Brazil on Wednesday [23 Dec 2020], the Secretariat of Health of Parana released a biweekly yellow fever bulletin recording 3 dead monkeys (epizootics) confirmed in the municipalities of Cruz Machado, Honorio Serpa, and Palmas.
The epidemiological period beginning in July 2020 totals 87 notifications of epizootic diseases: 11 were confirmed as the deaths of monkeys infected by yellow fever [virus]; 32 were discarded; 35

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PRO/AH/EDR> Undiagnosed illness - India (09): (TG) pesticide susp.

Undiagnosed -- India
[Please note, this is NOT Eluru's mystery illness. This is a different location with only 20 hospitalized people, not over 100 hospitalized and more than 600 affected as in Eluru. These individuals have different clinical signs than those in Eluru. - Mod.TG]
As many as 20 people belonging to Bajana thanda of Ayodya village were hospitalised on Fri 25 Dec 2020 after they experienced stomach pain and diarrhoea.
According to sources, around 102 persons belonging to the thanda have not been

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PRO/AH/EDR> Pigeon fever - Canada (BC): horse

Other Animal Disease -- Canada
Three forms of PF have been described in horses: external abscesses, internal infection, and ulcerative lymphangitis or limb infection. Ulcerative lymphangitis and internal infection must be treated more aggressively with antimicrobial therapy, while use of antimicrobials for external abscesses is generally unnecessary. _C. pseudotuberculosis_ produces various extracellular exotoxins which play a role in virulence and explain the presence of pain and edema at the site of infection.
External

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PRO/AH/EDR> Chronic wasting disease - North America (07): USA (MT) deer

Chronic Wasting Disease -- United States
The Blackfeet Fish and Wildlife Department was notified by Montana Fish, Wildlife and Parks (MFWP) that a tribal hunter harvested a whitetail deer from the Meriwether Road area on 11 Nov 2020, which tested positive for chronic wasting disease (CWD). The tribal hunter had voluntarily provided a sample to MFWP for CWD testing in Bozeman.
CWD is a fatal neurologic disease of moose, elk, whitetail deer, mule deer and caribou for which there is no known cure. It belongs to a group of diseases

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PRO/AH/EDR> Yersiniosis - Norway (02): lettuce

Foodborne Illness -- Norway
The source of infection of the national outbreak with _Yersinia enterocolitica_ is probably a pre-cut lettuce product, according to the investigation of the outbreak.
The outbreak is considered over. Lettuce has a short shelf life, and the relevant lettuce products are probably no longer on the market, says senior researcher Umaer Naseer at the National Institute of Public Health.
The outbreak of _Yersinia enterocolitica_ O3 started in mid-November 2020. In total, as of 21 Dec 2020,

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PRO/AH/EDR> Issyk-Kul virus - Germany: bat, 1st rep

Other Animal Disease -- Germany
Bats have been gaining attention as potential reservoir hosts of numerous viruses pathogenic to animals and man. Issyk-Kul virus, a member of the family _Nairoviridae_, was first isolated in the 1970s from vespertilionid bats in Central Asia. Issyk-Kul virus has been described as a human-pathogenic virus, causing febrile outbreaks in humans with headaches, myalgia and nausea. Here we describe the detection of a novel strain of Issyk-Kul virus from _Eptesicus nilssonii_ in Germany. This finding

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PRO/AH/EDR> Avian influenza, human (08): China (HN) H5N6, new case

Avian Influenza H5N6 -- China
According to the Hunan Provincial Center for Disease Control and Prevention, on the evening of 21 Dec 2020, a human case of H5N6 avian influenza was confirmed in Ningyuan County, Yongzhou City, Hunan Province. The patient is currently receiving treatment, and his vital signs are stable. Local live poultry trading has been suspended from 20 Dec 2020.
It is understood that the patient contracted the disease at a live poultry trading market in Ningyuan County. He was sampled on 19 Dec 2020 by

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PRO/AH/EDR> Newcastle disease - Russia (04): (CN) poultry, OIE

Newcastle Disease -- Russia
Information received on [and dated] 23 Dec 2020 from Dr. Nikolay Vlasov, Deputy Head, Federal Service for Veterinary and Phytosanitary Surveillance, Ministry of Agriculture, Moscow, Russia
Summary
Report type: Immediate notification
Date of start of the event: 7 Dec 2020
Date of confirmation of the event: 17 Dec 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: 29 Apr 2019
Manifestation of disease: Clinical disease
Causal agent: Newcastle

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PRO/AH/EDR> COVID-19 update (558): variants, Africa, Europe, Hong Kong, trials, WHO, global

COVID-19 -- Worldwide/Unknown
All our Nigerian SARS_CoV_2 sequences obtained from the beginning of the pandemic in Nigeria till date are available at . All of these sequences are also available on GISAID.
Partners and Collaborators
African Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University, Ede, Osun State, @acegid.
Redeemer's University, Ede, Osun State (RUN), @RedeemersUni
Nigeria Centre for Disease Control (NCDC), Abuja, Nigeria, @NCDCgov.
Africa Center for Diseases Control

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PRO/AH/EDR> Avian influenza (118): Russia (RO) HPAI H5, wild bird, OIE

Avian Influenza -- Russia
Information received on [and dated] 23 Dec 2020 from Dr Nikolay Vlasov, Deputy Head, Federal Service for Veterinary and Phytosanitary Surveillance, Ministry of Agriculture, Moscow, Russia
Summary
Report type: immediate notification
Date of start of the event: 17 Dec 2020
Date of confirmation of the event: 21 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 29 Mar 2017
Manifestation of disease: clinical disease
Causal agent: highly

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Saturday 26 December 2020

PRO/AH/EDR> Yellow fever - Africa (25): Guinea, WHO

Yellow Fever -- Guinea
Between 6 Nov and 15 Dec 2020, 52 suspected cases of yellow fever (YF), including 14 deaths, were reported in Guinea. A total of 50 cases were reported from the health district of Koundara in northwest Guinea, one from the health district of Dubreka (near Conakry, in the southwest), and one from the health district of Kouroussa, in the center of the country. Analysis performed at the Nongo, Conakry Laboratory of Viral Hemorrhagic Fevers revealed that 10 cases of suspected YF were IgM positive

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PRO/AH/EDR> COVID-19 update (557): animal, Slovenia (SA) ferret, OIE

COVID-19 -- Slovenia
Information received on [and dated] 23 Dec 2020 from Dr Breda Hrovatin, Head, Animal Health and Animal Welfare Division, Ministry of Agriculture, Forestry and Food, Ljubljana, Slovenia
Summary
Report type: immediate notification (final report)
Date of start of the event: 25 Nov 2020
Date of confirmation of the event: 1 Dec 2020
Reason for notification: emerging disease
Morbidity: 1%
Mortality: 0%
Zoonotic impact: no
Causal agent: SARS-CoV-2
New outbreaks (1)
Total outbreaks:

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PRO/AH/EDR> Salmonellosis - Finland

Salmonella -- Finland
Two different _Salmonella_ outbreaks have been reported in Finland with one linked to zucchini from Spain. The 1st outbreak, in the Finnish city of Rovaniemi, affected 20 people, but a source was not found. The 2nd incident, in the city of Mikkeli, led to 8 illnesses and was caused by contaminated chopped zucchini from Spain that was put in a salad.
Officials in Rovaniemi initially reported a suspected outbreak in early December 2020. Onset of symptoms for the 1st patients began on 17 Nov

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PRO/EDR> Shigellosis - India: (KL)

Shigellosis -- India
Authorities in Kozhikode district in Kerala went into high alert mode after a boy was found infected with the contagious _Shigella_ bacterium. Health Minister K.K. Shailaja has called upon the people to observe caution. Shailaja, however, maintained that the situation was under control and that the Health Department was geared up to face any eventuality.
The 1.5-year-old child was admitted to a private hospital in Kozhikode following complaints of acute stomach pain and diarrhea. Doctors

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PRO/AH/EDR> Yersiniosis - Norway

Not Yet Classified -- Norway
The Norwegian Institute of Public Health has discovered an increased incidence of the gastrointestinal bacterium _Yersinia enterocolitica_ O3. So far, infection has been detected in 10 people who live in several counties. Outbreak investigation has been initiated in collaboration with relevant municipal chief physicians, the Veterinary Institute and the Norwegian Food Safety Authority.
The patients are between 11 and 59 years old, and all are women. The infected live in Innlandet, Viken,

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PRO/AH/EDR> Salmonellosis, st Potsdam - USA: FDA

Salmonella -- United States
FDA's CORE Response Teams have published information about food poisoning outbreaks for the last month or so on their CORE Investigation Table. This table lists recent outbreaks caused by _E. coli_, _Salmonella_, _Listeria monocytogenes_, _Campylobacter_, and other pathogens. This table sometimes links to actionable steps for consumers to take, but it may not. At this time, there is no information about the potential food source for the new _Salmonella [enterica_ serotype] Potsdam

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PRO/AH/EDR> COVID-19 update (556): Egypt, UAE, Thailand, diabetes, mutations, WHO, global

COVID-19 -- Worldwide/Unknown
WHO region (no. countries/territories):
Total confirmed cases (new cases in last 24 hours) / Total deaths (new deaths in last 24 hours)
------------------------------------
Western Pacific Region (19): 1 043 191 (8637) / 19 397 (84)
European Region (61): 24 917 775 (245 610) / 548 256 (4266)
South East Asia Region (10): 11 779 854 (33 084) / 179 666 (564)
Eastern Mediterranean Region (22): 4 780 241 (24 537) / 118 097 (521)
Region of the Americas (54): 33 878 565 (323 507) / 831 672

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Friday 25 December 2020

PRO/AH/EDR> African swine fever - Europe (34): Russia (TT) wild boar

African Swine Fever -- Russia
Tatarstan isn't considered a safe region regarding the African swine fever [ASF] anymore, claimed vice head of the Main Veterinary Office of the Tatarstan Cabinet of Ministers, Gabdulkhak Motygullin, on 21 Dec [2020].
"I will start with the unpleasant news: a mortality case of wild boars in Yelabuga District was found on Saturday [19 Dec 2020]. Samples were taken; a laboratory showed the ASF. The samples were sent to the Federal Centre in Vladimir to confirm the diagnosis. We are waiting

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PRO/AH/EDR> COVID-19 update (555): USA (CO) animal, black-footed ferret, vaccine

COVID-19 -- United States
In late summer [2020], as researchers accelerated the 1st clinical trials of COVID-19 vaccines for humans, a group of scientists in Colorado worked to inoculate a far more fragile species. About 120 black-footed ferrets, among the most endangered mammals in North America, were injected with an experimental COVID vaccine aimed at protecting the small, weasel-like creatures rescued from the brink of extinction 4 decades ago.
The effort came months before US Department of Agriculture officials

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PRO/AH/EDR> COVID-19 update (554): Nigeria mutation, UK duration of immunity, WHO, global

COVID-19 -- Nigeria
Abstract
--------
Background
The relationship between the presence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains unclear.
Methods
We investigated the incidence of SARS-CoV-2 infection confirmed by polymerase chain reaction (PCR) in seropositive and seronegative health care workers attending testing of asymptomatic and symptomatic staff at Oxford University Hospitals in the United Kingdom. Baseline antibody

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PRO/AH/EDR> Undiagnosed deaths, buffalo - Taiwan: (Yangmingshan Natl Park) RFI

Undiagnosed -- China
A team composed of veterinarians and animal health specialists is now looking into 24 deaths of wild water buffaloes in Yangmingshan National Park, the Taipei City Animal Protection Office said Saturday [19 Dec 2020].
Among the 24 dead wild water buffaloes, the office noted 18 died over the past 19 days, including one calf that was found dead Friday evening [18 Dec 2020].
To determine the cause of deaths, the team recently collected samples from the carcasses as well as water and plants

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PRO/PL> Sclerotinia & blackleg, oilseed rape - Canada: (SK)

Other Plant Disease -- Canada
Sclerotinia (also called stem rot, white mould) of oilseed rape (_Brassica napus_; osr, "canola" refers to a group of specific varieties) is caused by _Sclerotinia sclerotiorum_. The fungus is one of the most nonspecific and successful of plant pathogens, with around 400 known hosts worldwide, including many crop species. It causes white fungal growth on aerial plant parts which leads to rotting, wilting and death of plants. On oilseed rape, infected leaves collapse around the stem, then stem

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Thursday 24 December 2020

PRO/AH/EDR> COVID-19 update (553): variants, immunocompromised, M East/N Africa, WHO, global

COVID-19 -- United Kingdom
This variant shares some similarities to the one that has already been detected in the UK, although they have evolved separately.
Both have a mutation -- called N501Y -- which is in a crucial part of the virus that it uses to infect the body's cells.
Prof Neil Ferguson, from Imperial College London, said: "I think the greatest concern of ours at the moment is the South African one.
"There's certainly anecdotal reports of explosive outbreaks for that virus and very steep increases in

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PRO/AH/EDR> Rabbit hemorrhagic disease - USA (10): (WY) wild rabbit

Other Animal Disease -- United States
According to the Wyoming Livestock Board, a wild eastern cottontail has tested positive for Rabbit Hemorrhagic Disease Virus 2 in Albany County.
The disease is a viral pathogen that causes sudden death in rabbits and can be spread through direct contact with infected rabbits, meat or fur, or materials that come in contact with those carriers. It is only known to affect rabbits, both wild and domestic. It is highly contagious, fatal, and is not related to coronavirus. It is not known to

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PRO/AH/EDR> Avian influenza (117): Japan, wild bird, HPAI H5N8, OIE

Avian Influenza H5N8 -- Japan
Information received on [and dated] 24 Dec 2020 from Dr. Norio Kumagai, Director, Chief Veterinary Officer, Animal Health Division, Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan
Summary
Report type: immediate notification
Date of start of the event: 3 Dec 2020
Date of confirmation of the event: 9 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 25 Mar 2018
Manifestation of disease:

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PRO/AH/EDR> Rhinotracheitis, bovine (IBR/IPV) - Switzerland: (GR) cattle, recurrence

Other Animal Disease -- Switzerland
Swiss authorities have identified a cow with the infectious bovine rhinotracheitis (IBR), a respiratory disease, in the eastern canton of Grisons [Graubunden], local officials said on [Wed 23 Dec 2020].
The disease, which is incurable in animals but harmless to humans, poses a threat to cattle. There have been no cases of IBR in Switzerland since 1993, the officials said [but see https://bit.ly/3nS2pwC and comment. - Mod.AS].
"In order to determine the possible spread

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PRO/AH/EDR> Ebola-Reston, porcine - Philippines: USA, pig, experimental infection trial

Ebola -- Philippines
Reston ebolavirus (RESTV) should be considered a livestock pathogen with potential to affect other mammals, including people, according to National Institutes of Health scientists. The caution comes from a study published in Proceedings of the National Academy of Sciences in which the scientists found that experimental piglets infected with RESTV developed severe respiratory disease and shed the virus from the upper respiratory tract. RESTV can infect humans but is not known to cause disease.

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PRO/AH/EDR> Avian influenza (116): Belgium (WV), poultry, LPAI H5 OIE

Avian Influenza -- Belgium
Information received on [and dated] 22 Dec 2020 from Dr. Herman Claeys, Head of the Health Policy Department: Animals and Plants, Directorate-General Animals, Plants and Food, Federal Public Health Service, Food Chain Safety and Environment, Brussels, Belgium
Summary
Report type: Immediate notification
Date of start of the event: 14 Dec 2020
Date of confirmation of the event: 17 Dec 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: 29 Jan

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Wednesday 23 December 2020

PRO/AH/EDR> COVID-19 update (552): USA, animal, cat, dog, snow leopard, OIE

COVID-19 -- United States
Information received on 21 Dec 2020 from Dr Mark Davidson, Associate Administrator, USDA-APHIS, United States Department of Agriculture, Washington, United States of America
Summary
Report type: immediate notification
Date of start of the event: 27 Mar 2020
Date of confirmation of the event: 4 Apr 2020
Report date: 18 Dec 2020
Date submitted to OIE: 21 Dec 2020
Reason for notification: emerging disease
Morbidity: 2 (scale 0 to 5)
Mortality: 1 (scale 0 to 5)
Zoonotic impact:

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PRO/AH/EDR> Avian influenza (115): Iran (TE) HPAI, poultry, H5N8, OIE

Avian Influenza H5N8 -- Iran
Information received on [and dated] 15 Dec 2020 from Dr. Ali Safar Maken Ali, Head, Iran Veterinary Organization (IVO), Ministry of Jihad-e-Agriculture, Tehran, Iran
Summary
Report type: Immediate notification
Date of start of the event: 5 Dec 2020
Date of confirmation of the event: 6 Dec 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: 28 Jan 2020
Manifestation of disease: Clinical disease
Causal agent: Highly pathogenic avian influenza

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PRO/AH/EDR> COVID-19 update (551): animal, pig, research, experimental infection

COVID-19 -- Worldwide/Unknown
In a study in Emerging Infectious Diseases late last week, Canadian and US researchers found that pigs are susceptible to SARS-CoV-2, the virus that causes COVID-19, highlighting the need for additional livestock assessment to determine the potential role of domestic animals in the pandemic.
Previous studies indicated that swine are not susceptible to SARS-CoV-2 infection, but they did not measure seroconversion (antibody production), the authors note.
They inoculated 19 eight-week-old

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PRO/AH/EDR> COVID-19 update (550): mutation, query, Thailand, Taiwan, WHO, global, RFI

COVID-19 -- Thailand
Executive summary
-----------------
A new variant strain of SARS-CoV-2 that contains a series of mutations has been described in the United Kingdom (UK) and become highly prevalent in London and southeast England. Based on these mutations, this variant strain has been predicted to potentially be more rapidly transmissible than other circulating strains of SARS-CoV-2. Although a variant may predominate in a geographic area, that fact alone does not mean that the variant is more infectious.

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PRO/AH/EDR> Avian influenza (114): UK, Germany, poultry, wild bird, HPAI H5N1, H5N3, OIE

Avian Influenza H5N1 -- United Kingdom
Information received on [and dated] 18 Dec 2020 from Dr Christine Middlemiss, Chief Veterinary Officer, DEFRA, Department for Environment, Food and Rural Affairs, London, United Kingdom
Summary
Report type: immediate notification
Date of start of the event: 13 Dec 2020
Date of confirmation of the event: 18 Dec 2020
Reason for notification: new strain of a listed disease in the country
Causal agent: Highly pathogenic avian influenza [AI] virus
Serotype: H5N1
Nature of diagnosis:

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Tuesday 22 December 2020

PRO/AH/EDR> Ehrlichiosis - Australia (04): (NT) dogs

Other Animal Disease -- Australia
Nearly 1000 dogs may have already died from an exotic tick-borne disease rapidly spreading through remote indigenous communities, according to a Top End vet.
Ehrlichiosis was believed not to exist in Australia until it was confirmed in WA's Kimberley region in May 2020 and the Northern Territory in June 2020.
The bacterial disease causes fever, lethargy, enlarged lymph nodes, under-skin bleeding, weight loss, and can lead to death in dogs.
Bonny Cumming, a vet with Animal Management

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PRO/AH/EDR> COVID-19 update (549): animal, mink, Denmark, erad. Russia, vaccine, China, RFI

COVID-19 -- Denmark
Denmark on Monday [21 Dec 2020] banned mink farming until the start of 2022 after it emerged that a strain of the coronavirus can be passed between the animals and humans.
Officials have concerns that the mutated variant could threaten the effectiveness of future vaccines.
The draft bill passed by 55 votes to 43 in parliament with the main opposition parties -- the central-right Liberals and the populist Danish People's Party -- voting against the bill.
"Danish mink farmers have

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PRO/AH/EDR> Undiagnosed illness - India (08): (AP) fatal, further investigations

Undiagnosed -- India
All India Institute of Medical Sciences (AIIMS) and National Institute of Chemical Technology (NICT) in a report to the Andhra Pradesh government stated that pesticide remains could be the cause of the disease which affected the people of Eluru. How it entered their bodies should be further investigated.
Andhra Pradesh Chief Minister YS Jagan Mohan Reddy held a video conference on the cause of illness in Eluru with experts. The CM said all types of tests should be conducted so incidents

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PRO/EDR> Poliomyelitis update (23): Afghanistan (KT, PK), RFI

Polio -- Afghanistan
Six polio cases have been reported in the southeastern zone after a long time, public health officials say, expressing their concern about the cases. They said 5 of the cases were detected in Khost and one in Paktika province.
Dr. Habib, an official at the Immunization Regional Office, said he was in touch with the Public Health Ministry and provincial officials to prevent an increase in polio cases.
He said some people were reluctant to vaccinate their children based on various rumors

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PRO/AH/EDR> Bovine tuberculosis - Belgium: (LG) cattle, OIE

Bovine TB -- Belgium
Information received on [and dated] 21 Dec 2020 from Dr Herman Claeys, Chef du Service Politique sanitaire: Animaux et Vegetaux, Directorat-general Animaux, Vegetaux et Alimentation, Service Public Federal Sante publique, securite de la chaine alimentaire et environnement, Bruxelles, Belgium
Summary
Report type: immediate notification
Date of start of the event: 16 Nov 2020
Date of confirmation of the event: 18 Dec 2020
Reason for notification: reoccurrence of a listed disease
Date of

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PRO/AH/EDR> COVID-19 update (548): mutations, PEGs,Thailand, WHO, global

COVID-19 -- Thailand
On [14 Dec 2020], authorities of the United Kingdom (UK) reported to WHO that a new SARS-CoV-2 variant was identified through viral genomic sequencing. This variant is referred to as SARS-CoV-2 VUI 202012/01 (variant under investigation, year 2020, month 12, variant 01). Initial analysis indicates that the variant may spread more readily between people. Investigations are ongoing to determine if this variant is associated with any changes in the severity of symptoms, antibody response, or

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PRO/PL> Ralstonia, potato, & tomato - Germany: (BY) alert

Other Plant Disease -- Germany
Farmers along the Naab River in the upper palatinate region of Bavaria may no longer irrigate their potatoes and tomatoes with river water. The Naab upwards from where it joins the Danube is contaminated with _Ralstonia solanacearum_, bacteria that cause dangerous slime rots of those crops.
The pathogen spreads quickly and destroys potato and tomato crops. It is, therefore, classified as a quarantine disease by the European Union. Affected farmers will suffer serious yield losses, as well

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Monday 21 December 2020

PRO/PL> Undiagnosed disease, orange - India: (SK)

Undiagnosed -- India
An unknown disease has claimed around 70% of oranges in [parts of] East District. A local farmer [said] that flowering and fruiting of the oranges were excellent this [2020] season. However, the oranges were just about ready for plucking when the fruits started dropping, he said. Around 70-90% of the orange production has been lost. The farmers are presently collecting the fallen semi-ripe oranges. "We are burying our damaged oranges because it could infect our fruit-bearing trees. We do not

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PRO/AH/EDR> Hantavirus - Asia (05): China (SA)

Hantavirus -- China
Recently, a 16-year-old girl was admitted to Xi'an Children's Hospital due to sudden haemorrhagic fever. She was in the intensive care unit for a week because of her serious condition before she got better.
The girl (ZZ) ate out on the day of the incident. She ate 3 steamed buns and a bowl of rice noodles. She developed fever after returning home. The fever reached 39 C [102 F]. The family rushed her to the county hospital, and then she was transferred to Xi'an Children's

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PRO/AH/EDR> COVID-19 update (547): mutations, travel restrictions, Thailand, WHO, global

COVID-19 -- Thailand
The aim of this Threat Assessment Brief is to summarise the findings, assess potential public health implications of this new variant, provide options for response and point out limitations, unknowns, and needs for further studies and investigations.
Executive summary
-----------------
Over the last few weeks, the United Kingdom (UK) has faced a rapid increase in COVID-19 cases in South East England, leading to enhanced epidemiological and virological investigations. Analysis of viral

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Sunday 20 December 2020

PRO/AH/EDR> COVID-19 update (546): animal, Sweden, mink, surveillance, spread, control, RFI

COVID-19 -- Sweden
[An e-mail from Sweden's Veterinary Service to OIE's Information Department, dated 1 Dec 2020]:
In the framework of the ongoing surveillance in Swedish mink farms, the National Veterinary Institute (SVA) has confirmed 3 further cases of infection with SARS-CoV-2 in mink farms in the southeast part of the country, in the county of Blekinge.
All positive farms are in the same area as the 1st case detected, in which approximately 20 of Sweden's 40 mink farms are situated. In total, there

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PRO/EDR> Poliomyelitis update (22): Pakistan (BA)

Polio -- Pakistan
Another polio case has been reported in Balochistan, taking the tally of the cases for the current year [2020] to 25 in the province, ARY News reported.
The provincial health department has confirmed that a 16-month-old boy in Qila Abdullah area of the province tested positive for the virus. With the latest inclusion, the overall number of poliovirus cases in Balochistan has jumped to 25. Earlier on [25 Sep 2020], a polio case had been reported in Ahmedpur East tehsil in Punjab's Bahawalpur

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PRO/AH/EDR> Chronic wasting disease - North America (06): USA (WY) elk

Chronic Wasting Disease -- United States
An elk has tested positive for chronic wasting disease in an area of northwestern Wyoming where the animals congregate during the winter at feeding grounds.
Wyoming's Wildlife Health Laboratory processed a test Wednesday [16 Dec 2020] from an elk killed by a hunter as part of Grand Teton National Park's annual elk population control efforts, state officials announced Friday [18 Dec 2020].
Mule deer and moose have tested positive for chronic wasting disease in the area in the past, but

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PRO/AH/EDR> COVID-19 update (545): mutations, UK, South Africa, South Asia, WHO, global

COVID-19 -- United Kingdom
WHO region (no. countries/territories):
Total confirmed cases (new cases in last 24 hours) / Total deaths (new deaths in last 24 hours)
------------------------------------
Western Pacific Region (19): 999 891 (7958) / 18 798 (90)
European Region (61): 23 457 397 (265 890) / 518 481 (5792)
South East Asia Region (10): 11 572 247 (35 166) / 176 277 (543)
Eastern Mediterranean Region (22): 4 641 968 (25 244) / 114 971 (518)
Region of the Americas (54): 31 925 704 (352 665) / 804 012

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PRO/AH/EDR> Equine influenza - USA (08): (CA) horse

Equine Influenza -- United States
A Los Angeles, California boarding facility remains closed to ingress and egress after an attending veterinarian confirmed equine influenza in 2 ponies. 25 additional equines are suspected as positive, and 120 were exposed.
The affected animals, an 18-year-old Welsh pony mare and a 16-year-old Welsh pony gelding, were both under-vaccinated. The mare began experiencing signs, which included fever and cough, on 10 Dec 2020 and was confirmed positive on 16 Dec 2020. The gelding began showing

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Saturday 19 December 2020

PRO/AH/EDR> Avian influenza (113): UK, poultry, captive bird, HPAI H5N8, spread, control

Avian Influenza H5N8 -- United Kingdom
A flock of chickens from an Orkney farm has been culled in Scotland's 1st serious case of bird flu since 2016. A 6-mile (10 km) control zone has been set up on the island of Sanday. Thirty-nine free-range laying chickens died of bird flu, and the 11 remaining birds in the affected flock were put down.
The controls include restrictions on the movement of poultry, carcasses, eggs, used poultry litter and manure, and restrictions on bird gatherings.
Scotland's Chief Veterinary Officer

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PRO/AH/EDR> Avian influenza (113): UK, poultry, captive bird, HPAI H5N8, spread, control

Avian Influenza H5N8 -- United Kingdom
A flock of chickens from an Orkney farm has been culled in Scotland's 1st serious case of bird flu since 2016. A 6-mile (10 km) control zone has been set up on the island of Sanday. Thirty-nine free-range laying chickens died of bird flu, and the 11 remaining birds in the affected flock were put down.
The controls include restrictions on the movement of poultry, carcasses, eggs, used poultry litter and manure, and restrictions on bird gatherings.
Scotland's Chief Veterinary Officer

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PRO/AH/EDR> Epizootic hemorrhagic disease, cattle - Israel (02): (HZ,HM) spread, st pend, OIE

Epizootic Hemorrhagic Disease -- Israel
Information received on [and dated] 12 Dec 2020 from Dr. Tamir Goshen, Acting Director, Veterinary Services and Animal Health, Ministry of Agriculture and Rural Development, Beit Dagan, Israel
Summary
Report type: Follow-up report no. 4
Date of start of the event: 14 Oct 2020
Date of confirmation of the event: 8 Nov 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: October 2016
Manifestation of disease: Clinical disease
Causal agent: Epizootic

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PRO/AH/EDR> Invasive mosquito - USA (10): (FL)

Other Human Disease -- United States
_Aedes scapularis_ is a mosquito that can spread yellow fever, Venezuelan equine encephalitis virus, and other human pathogens. It has a wide range, from Texas to parts of South America and throughout much of the Caribbean. In 1945, 3 specimens of larval _Ae. scapularis_ were found in Monroe County, Florida, in the Middle Florida Keys, but _Ae. scapularis_ has not been seen in Florida since then -- until now. A new study published in November [2020] in the Journal of Medical Entomology by

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PRO/AH/EDR> Contagious bovine pleuropneumonia - Niger: (TL) OIE

Bovine Pleuropneumonia -- Niger
Information received on [and dated] 15 Dec 2020 from Dr. Issiako Abdou, Director General of Veterinary Services, Department of Animal Health, Ministry of Agriculture and Livestock, Niamey, Niger
Summary
Report type: Immediate notification
Date of start of the event: 3 Dec 2020
Date of confirmation of the event: 6 Dec 2020
Report date: 15 Dec 2020
Date submitted to OIE: 15 Dec 2020
Reason for notification: 1st occurrence of a listed disease
Manifestation of disease: Clinical

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PRO/AH/EDR> COVID-19 update (544): mAb cocktail, mortality, Thailand, WHO, global

COVID-19 -- Worldwide/Unknown
Background: Recent data suggest that complications and death from coronavirus disease 2019 (COVID-19) may be related to high viral loads.
Methods: In this ongoing, double-blind, phase 1-3 trial involving nonhospitalized patients with COVID-19, we investigated 2 fully human, neutralizing monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, used in a combined cocktail (REGN-COV2) to reduce the risk of the emergence of treatment-resistant

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Friday 18 December 2020

PRO/AH/EDR> Lassa fever - West Africa (24): Nigeria

Lassa Fever -- Nigeria
Key points:
Current week (50) (7-13 Dec 2020) / Cumulative weeks 1-50 / Cumulative 2019 weeks 1-50
Suspected cases: 55 / 6590 / 4897
Confirmed cases: 5 / 1163 / 810
Probable cases: 0 / 14 / 19
Deaths: 1 / 241 / 167
Case fatality rate (CFR [%]): 20.0 / 20.7 / 20.6
Number of states affected: 3 / 27 / 23
Local government areas (LGAs) affected: 5 / 130 / 86
Highlights
- In week 50, the number of new confirmed cases increased from 4 in week 49, 2020, to 5 cases. These were reported

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PRO/AH/EDR> Avian influenza (112): UK, wild bird, HPAI H5N5

Avian Influenza -- United Kingdom
Bird flu has been reported in different animals in 2 parts of Wales as a high alert warning has been issued across the UK.
Newport City Council posted that wild geese and swans in the city had tested positive for the "highly pathogenic avian influenza HPAI H5N5". The Department of Environment, Food & Rural Affairs (Defra) has also said a case has been reported in the past week [7-13 Dec 2020] in a little grebe, a type of water bird, in Carmarthenshire.
Nearly 150 cases have been reported

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PRO/AH/EDR> COVID-19 update (543): vaccine, excess mortality, Nigeria, India, WHO, global

COVID-19 -- Nigeria
"Coronavirus disease 2019 (COVID-19) has caused a marked increase in all-cause deaths in the US, mostly among older adults./1 Although the burden of COVID-19 among hospitalized younger adults has been described, fewer data focus on mortality in this demographic, owing to lower case-fatality rates./2
"Excess mortality reflects the full burden of the pandemic that may go uncaptured due to uncoded COVID-19 and other pandemic-related deaths. Accordingly, we examined all-cause excess mortality

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PRO/PL> Rhizoctonia, cereal crops - Australia: (WA)

Other Plant Disease -- Australia
Increased rhizoctonia bare patches in cereals have been observed around WA [Western Australia] this [2020] season. Daniel Hueberli, Department of Primary Industries and Regional Development WA (DPIRD), said the main reason for the higher levels of rhizoctonia was late rain and the subsequent later emergence of crops in a lot of regions.
"The 2nd reason was that growers were likely sowing into a high inoculum load, most of the paddocks probably had some cereals in there previously. We also

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PRO/AH/EDR> COVID-19 update (542): animal, Greece (EM) mink mutation, human, OIE

COVID-19 -- Greece
Information received on [and dated] 15 Dec 2020 from Mrs Chrysoula Dile, Head, Animal Health Directorate, Ministry of Rural Development and Food, Athens, Greece
Summary
Report type: immediate notification
Date of start of the event: 4 Dec 2020
Date of confirmation of the event: 8 Dec 2020
Reason for notification: emerging disease
Morbidity: 2 (scale 0 to 5)
Mortality: 1 (scale 0 to 5)
Zoonotic impact: The Y453F mutation in the spike (S) protein of the virus, referred to as

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PRO/AH/EDR> Avian influenza (111): Europe, poultry, captive/wild bird, H5N1, H5N5, H5N8, OIE

Avian Influenza H5N1, Avian Influenza H5N8, Avian Influenza -- Netherlands
Information received on [and dated] 16 Dec 2020 from Dr. Christianne Bruschke, Chief Veterinary Officer, Agriculture, Nature and Food Quality, Ministry of Agriculture, Nature and Food Quality, The Hague, Netherlands
Summary
Report type: immediate notification
Date of start of the event: 14 Dec 2020
Date of confirmation of the event: 14 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 10 Jul 2018
Manifestation of disease: clinical

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Thursday 17 December 2020

PRO/PL> Verticillium wilt, oilseed rape - Canada: (SK)

Other Plant Disease -- Canada
Verticillium stripe appears to be making its way west, as some fields in Saskatchewan showed symptoms this [2020] summer as well. [The] soil-borne disease, 1st detected in Manitoba in 2014 [ProMED-mail post https://bit.ly/2IZpy0K], caused yield losses in 2020 canola crops.
It is found in Europe and Australia and, because it was detected so recently, very little Canadian research has been completed. According to Justine Cornelsen, Canola Council of Canada, it was called

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PRO/EDR> Poliomyelitis update (21): global, Sierra Leone, RFI

Polio -- Sierra Leone
[The data presented here comes from the GPEI weekly report email and is in discord with the website. It is unclear which are the correct figures. To be clarified in the coming days. - Mod.MPP]
Poliovirus weekly update as of 16 Dec 2020, World Health Organization
New wild poliovirus isolates reported this week:
AFP cases: 0
Environment: 3
Others: 0
New cVDPV isolates reported this week:
AFP cases: 68
Environment: 3
Others: 13
Headlines:
- The EB [executive board] reports on

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PRO/AH/EDR> Undiagnosed die-off, avian - USA: (ID) duck, RFI

Animal Die-off -- United States
The number of dead ducks found south of Salmon has more than doubled as wildlife officials continue to collect carcasses and search for a cause. Idaho Fish and Game biologist Tempe Regan reported finding a total of 107 dead ducks since last week [7-13 Dec 2020] along an irrigation ditch and in adjacent sloughs and ponds south of town. Initially, about 50 dead birds were found.
Fish and Game's Mike Demick said 6 ducks were sent to be tested at the National Wildlife Health Center and arrived

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PRO/AH/EDR> Undiagnosed die-off, avian - USA: (ID) duck, RFI

Animal Die-off -- United States
The number of dead ducks found south of Salmon has more than doubled as wildlife officials continue to collect carcasses and search for a cause. Idaho Fish and Game biologist Tempe Regan reported finding a total of 107 dead ducks since last week [7-13 Dec 2020] along an irrigation ditch and in adjacent sloughs and ponds south of town. Initially, about 50 dead birds were found.
Fish and Game's Mike Demick said 6 ducks were sent to be tested at the National Wildlife Health Center and arrived

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PRO/EDR> COVID-19 update (541): COVI-VAC, prevalence, fungal infections, WHO, global

COVID-19 -- Worldwide/Unknown
Summary
-------
Background
Decisions about the continued need for control measures to contain the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rely on accurate and up-to-date information about the number of people testing positive for SARS-CoV-2 and risk factors for testing positive. Existing surveillance systems are generally not based on population samples and are not longitudinal in design.
Methods
Samples were collected from individuals aged 2 years and

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PRO/AH/EDR> Measles update (29): Africa (DRC)

Measles -- DR Congo
Measles DR Congo: MSF says 183 837 cases causing 3667 deaths
A. Situation analysis
Description of the disaster
The DRC's Ministry of Health declared a measles outbreak in the country on 10 Jun 2019, presenting it as the deadliest outbreak in the country since the 2010-2011 outbreak which caused at least 210 deaths according to Médecins Sans Frontières. The epidemic spread rapidly to all 26 provinces of the country, exposing an unprecedented 9 110 984 people, affecting 183 837 people,

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Wednesday 16 December 2020

PRO/AH/EDR> Eastern equine encephalitis - North America (26): USA (SC) horse

Eastern Equine Encephalitis -- United States
Officials at Clemson Livestock Poultry Health (CLPH) have confirmed a 15-year-old Shetland pony mare with Eastern equine encephalomyelitis (EEE). The mare, which resided in Clarendon County, was unvaccinated and is deceased.
This is Clarendon County's 1st case of EEE in an equine this year [2020], and South Carolina's 17th.
Eastern equine encephalomyelitis is caused by the Eastern equine encephalitis virus, for which wild birds are a natural reservoir. Mosquitoes that feed on

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PRO/AH/EDR> COVID-19 update (540): S Africa MIS-C, USA risk factors, Iran serosurvey, WHO global

COVID-19 -- United States


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PRO/AH/EDR> Chronic wasting disease - North America (05): USA (OH) deer

Chronic Wasting Disease -- United States
The 1st positive case of chronic wasting disease has been reported in Ohio, according to the Ohio Department of Natural Resources (ODNR).
The positive test came from a white-tailed deer in Wyandot County northwest of Columbus.
The deer was shot by a hunter on private property, ODNR says. Tissue samples submitted by a taxidermist returned a positive result [10 Dec 2020].
CWD is a fatal neurological disease affecting white-tailed deer and other similar species such as mule deer, elk,

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Tuesday 15 December 2020

PRO/AH/EDR> Avian influenza (110): poultry, HPAI, Japan, H5, South Korea (CN) H5N8, spread

Avian Influenza H5N8 -- Japan
Japan has reported outbreaks of H5 highly pathogenic avian influenza (HPAI) in poultry [in the following municipalities/prefectures, namely in] Saeki city, Oita prefecture [date of confirmation, 10 Dec 2020], Kinokawa city, Wakayama prefecture [date of confirmation, 10 Dec 2020], Mimasaka city, Okayama prefecture [date of confirmation, 11 Dec 2020], and Higashiomi city, Shiga prefecture [date of confirmation, 13 Dec 2020].
--
Communicated by:
ProMED-mail

[The said information was

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PRO/AH/EDR> Poliomyelitis update (20): Sierra Leone, cVDPV

Polio -- Sierra Leone
Sierra Leone's Minister of Health, Dr. Alpha Wurie, has confirmed 3 new polio cases in Sierra Leone for the 1st time in 10 years. He said the cases were recorded in Kambia, Tonkolili, and Western Area Rural District. The minister, however, said that the cases were not from the wild poliovirus strain, rather vaccine derived.
Asked how they were able to piece that together, Dr Wurie said that the samples were tested abroad and proved traceable to vaccines.
The confirmation comes a day

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PRO/AH/EDR> Foot & mouth disease - South Africa (02): (LP) cattle, serotype SAT 1, OIE

Foot and Mouth -- South Africa
Information received on [and dated] 13 Dec 2020 from Dr. Bothle Michael Modisane, chief director, Department of Agriculture, Forestry and Fisheries, Animal Production and Health, Pretoria, South Africa
Summary
Report type: immediate notification
Date of start of the event: 3 Sep 2020
Date of confirmation of the event: 2 Oct 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 30 Apr 2019
Manifestation of disease: sub-clinical infection
Causal

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PRO/AH/EDR> Avian influenza, human (07): China (JS) H5N6

Avian Influenza H5N6 -- China
Chinese health authorities report a human case of avian influenza A(H5N6) in an 81-year-old female farmer from Changzhou of Jiangsu Province.
The individual had exposure to live chickens at home prior to developing symptoms on [16 Nov 2020]. She was hospitalized and subsequently passed away on [27 Nov 2020].
From 2014 to date, 25 human cases of avian influenza A(H5N6) have been reported by the Chinese health authorities.
Avian influenza is caused by those influenza viruses that mainly

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PRO/AH/EDR> COVID-19 update (539): UK new variant, genomic study on severity, WHO, global

COVID-19 -- United Kingdom
"Host-mediated lung inflammation is present(1), and drives mortality(2), in critical illness caused by Covid-19. Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development.(3) Here we report the results of the GenOMICC (Genetics of mortality in critical care) genome-wide association study(GWAS) in 2244 critically ill COVID-19 patients from 208 UK intensive care units (ICUs). We identify and replicate novel genome-wide significant

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Monday 14 December 2020

PRO/PL> Wart disease, potato - Netherlands: (GR) new strain

Other Plant Disease -- Netherlands
An unknown variant of potato wart was discovered in Stadskanaal [Groningen province]. According to the NVWA [Netherlands Food and Consumer Product Safety Authority], the new variant may have consequences for the control of wart disease in the northeast of the Netherlands. It is still unclear whether potato varieties with good resistance to the known forms of wart disease are also resistant to the variant. The NVWA is investigating the origin of the infection and the possibilities for a

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PRO/AH/EDR> Avian influenza (109): Ireland, Germany, poultry, wild bird, HPAI H5N8, OIE

Avian Influenza H5N8 -- Ireland
Information received on [and dated] Fri 11 Dec 2020 from Dr. Martin Blake, Chief Veterinary Officer, Department of Agriculture, Food and the Marine, Agriculture House, Dublin, Ireland
Summary
Report type: Immediate notification
Date of start of the event: 9 Dec 2020
Date of confirmation of the event: 10 Dec 2020
Reason for notification: First occurrence of a listed disease in the country
Causal agent: Highly pathogenic avian influenza [AI] virus
Serotype: H5N8
Nature of diagnosis:

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PRO/AH/EDR> Avian influenza (108): Netherlands, poultry, LPAI H5 OIE

Avian Influenza -- Netherlands
Information received on [and dated] 14 Dec 2020 from Dr. Christianne Bruschke, Chief veterinary officer, Agriculture, Nature and Food Quality, Ministry of Agriculture, Nature and Food Quality, The Hague, Netherlands
Summary
Report type: immediate notification
Date of start of the event: 4 Dec 2020
Date of confirmation of the event: 9 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: 8 Mar 2018
Manifestation of disease: sub-clinical

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PRO/AH/EDR> COVID-19 update (538): USA, animal, zoo, snow leopard

COVID-19 -- United States
Another big cat species tested positive for coronavirus, this time a snow leopard. It's the 6th animal species confirmed to have been infected with the virus after human contact.
Three snow leopards, 2 males and a female, tested positive for the virus at the Louisville Zoo [Kentucky], the zoo and the US Department of Agriculture's Animal and Plant Health Inspection Service confirmed Friday [11 Dec 2020].
The female's infection was confirmed first. All 3 leopards, whose symptoms are

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PRO/AH/EDR> COVID-19 update (537): clinical trial, South Asia, comment, WHO, global

COVID-19 -- Afghanistan
Abstract
--------
Background
Severe coronavirus disease 2019 (COVID-19) is associated with dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, plus remdesivir are not known.
Methods
We conducted a double-blind, randomized, placebo-controlled trial evaluating baricitinib plus remdesivir in hospitalized adults with COVID-19. All the patients received remdesivir (10 days or less) and either baricitinib (14 days or less) or placebo

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PRO/PL> Undiagnosed disease, cassava - Uganda: (NB)

Undiagnosed -- Uganda
Cassava farmers in Nebbi District are counting losses after a strange disease destroyed their plantations. The district production officer said the cassava could have been attacked by both brown streak and soft root diseases, with about 40 percent of 647 registered farmers affected.
The farmers were mobilised in 2018 to plant Nasse-19, a cassava variety which matures in [approximately 18 months], with the aim of supplying factories. But the project has been beset by a number of challenges.

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Sunday 13 December 2020

PRO/AH/EDR> COVID-19 update (536): animal, USA (UT) wild mink, 1st case

COVID-19 -- United States


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PRO/AH/EDR> COVID-19 update (535): Denmark, animal, mink, zoonotic, cat, RFI

COVID-19 -- Denmark
After a few weeks with many newly infected persons residing on mink farms (production or owner addresses), where as many as 8% (260 persons) were tested positive during weeks 46 and 47, there has been a marked decrease in the number of persons residing on mink farms infected with SARS-CoV-2. This is shown in the latest situation update by the Statens Serum Institut (SSI).
According to the memo, the number of newly infected persons associated with mink production fell to 28 in week 48

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PRO/AH/EDR> COVID-19 update (534): tests, data, therapy, vaccines, WHO, global

COVID-19 -- Worldwide/Unknown
Coronavirus lateral flow tests only pick up 49 per cent of infections because they fail to catch people with low levels of the virus, researchers have found.
The findings of a pilot of 3199 people has blown a hole in the government's mass testing strategy, which featured plans to hand out millions of 30-minute tests to allow Britons to go back to living life normally, it was revealed yesterday [11 Dec 2020].
The lateral flow test, produced by US-based Innova, only picks up 48.89 per cent

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Saturday 12 December 2020

PRO/AH/EDR> Equine infectious anemia - North America (06): USA (TX) horse

Equine Infectious Anemia -- United States
Texas Animal Health Commission (TAHC) officials have confirmed 4 cases of equine infectious anemia (EIA) in the state: 2 in Harris County, 1 in Ector County, and 1 in Johnson County. All cases involved Quarter Horses.
All premises involved are under official quarantine until TAHC's requirements have been met. TAHC staff continue to work with owners and attending veterinarians to monitor horses that were potentially exposed, and to enact enhanced biosecurity protocols.
About EIA
Equine

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PRO/AH/EDR> Chronic wasting disease - North America (04): USA (MT) deer

Chronic Wasting Disease -- United States
Deadly, always fatal, and much feared, chronic wasting disease has now been confirmed in deer roaming both the Gallatin and Paradise valleys, and state wildlife officials are also concerned about a major emerging hotspot for disease along the lower Ruby River. [CWD appears not to have been found in these areas previously. - Mod.TG]
The arrival of CWD in big game animals around southwest Montana, a prominent part of the Greater Yellowstone ecosystem, is certain to cause many to wonder how

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PRO/EDR> Poliomyelitis update (19): comment

Polio -- Worldwide/Unknown


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PRO/AH/EDR> Equine herpesvirus - North America (10): USA (CA) horse

Equine Herpes Virus -- United States
A barn in Ventura County, California, has been quarantined after a mare developed neurologic signs associated with equine herpesvirus-1 (EHV-1), according to information supplied by the Equine Disease Communication Center (EDCC).
The 13-year-old Quarter Horse mare is in isolation at a local veterinary clinic for treatment while 32 potentially exposed horses at her home barn have been quarantined with extra biosecurity measures put in place. No additional cases have been identified as of

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PRO/AH/EDR> COVID-19 update (533): Italy 2019, USA reinfection, USA vaccine, WHO, global

COVID-19 -- Worldwide/Unknown
Patient is a 39-year-old white male, A-negative blood type, seen in July 2020 for anxiety, states otherwise healthy, had complained of a "SARS-like" illness in February 2020, with symptoms of mild fever, body aches and impaired smell. Patient recovered after 2 weeks of just self-supportive care. [When seen in July 2020] was noted to have a normal Chem 21 panel, CBC, and a positive SARS-CoV-2 IgG on serum lab [serum sent to 2 different commercial labs: 1 was positive for SAR-CoV-2 IgG, the

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PRO/AH/EDR> Undiagnosed hemorrhagic fever - China (03): (SA)

Hemorrhagic Fever -- China
Today (9 Dec [2020]), the First News reporter learned from the Office of Health Care in Linwei District, Weinan City, that there have recently been more cases of hemorrhagic fever in the district, causing harm to people's production, life, and health. In order to reduce the incidence of hemorrhagic fever and effectively control the occurrence of rodent-borne diseases, the Patriotic Health Office will carry out concentrated rodent-control activities in many places in Linwei District.
Rodent

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Friday 11 December 2020

PRO/AH/EDR> Infectious hypodermal & hematopoietic necrosis - UK: (England) shrimp, OIE

Other Animal Disease -- United Kingdom
Information received on [and dated] 4 Dec 2020 from Dr Christine Middlemiss, chief veterinary officer, DEFRA (Department for Environment, Food and Rural Affairs), London, United Kingdom
Summary
Report type: immediate notification
Date of start of the event: 30 Oct 2020
Date of confirmation of the event: 3 Dec 2020
Reason for notification: recurrence of a listed disease
Date of previous occurrence: December 2019
Causal agent: infectious hypodermal and hematopoietic necrosis virus

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PRO/AH/EDR> Avian influenza (107): Poland, UK, wild bird, HPAI H5N8, H5N5, OIE

Avian Influenza H5N8, Avian Influenza -- Poland
Information received on [and dated] 10 Dec 2020 from Dr. Bogdan Konopka, Chief Veterinary Officer, Ministry of Agriculture and Rural Development, General Veterinary Inspectorate, Warsaw, Poland
Summary
Report type: Immediate notification
Date of start of the event: 8 Dec 2020
Date of confirmation of the event: 9 Dec 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: 7 Jan 2020
Manifestation of disease: Clinical disease
Causal agent: Highly

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PRO/AH/EDR> COVID-19 update (532): Turkey, USA vaccine, Australia vaccine trial, WHO, global

COVID-19 -- Turkey
The vaccine had been in stage one of trials, and proving to be effective in making antibodies. But it also generated HIV antibodies in some recipients -- which meant it showed false positives for HIV. Further testing proved the HIV wasn't there. CSL and UQ said fixing the flaw would take about a year, prompting a decision to abandon the trial. "It was likely to work. But we knew that we didn't want to have any issues with confidence, and this false-positive test may have caused some confusion

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PRO/EDR> Poliomyelitis update (18): cVDPV2 (Pakistan, CAR, Chad, Somalia), nOPV2

Polio -- Pakistan
[The data presented here comes from the GPEI weekly report email and is in discord with the website. It is unclear which are the correct figures. To be clarified in the coming days. - Mod.MPP]
As of 9 Dec 2020:
New wild poliovirus isolates reported this week:
AFP cases: 0
Environment: 5
Others: 0
New cVDPV isolates reported this week:
AFP cases: 17
Environment: 8
Others: 4
Headlines
- Aidan O'Leary appointed new WHO polio eradication director: Mr Aidan O'Leary will assume the

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PRO/AH/EDR> Anthrax - India (07): (AS) livestock vaccination

Anthrax -- India
The authorities in eastern Assam's Dibrugarh district have undertaken a drive to vaccinate livestock around the Joypur rainforest after anthrax was confirmed as the cause of the death of 2 female elephants a week ago.
This is the 2nd case of anthrax in [Assam] after 2 Asiatic water buffaloes died in the Pobitora Wildlife Sanctuary in October 2019 [see Anthrax - India (09): (AS) Pobitora Wildlife Sanctuary, buffalo https://bit.ly/3qQzaMe]. The sanctuary, 48 km (about 30

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PRO/AH/EDR> Yellow fever - Americas (13): Brazil (PR) monkey

Yellow Fever -- Brazil
The state Health Department on Wednesday [9 Dec 2020] confirmed the deaths of 8 monkeys from yellow fever virus infection. These cases occurred in Clevelandia (2 cases), Coronel Domingos Soares (3), Mangueirinha (1), and Cruz Machado (2).
Parana state in Brazil has registered to date since 1 Jul [2020] 81 notifications of monkeys dead of the virus. Of these, 11 cases are under investigation, 32 occurred for indeterminate causes, 30 were discarded [as yellow fever cases], and 8 were

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PRO/AH/EDR> Ebola update (54): neonatal survival after monoclonal antibody treatment, 2019

Ebola -- DR Congo
Doctors Without Borders/Médecins Sans Frontiéres' (MSF) case studies published in The Lancet this month [see [2] below] examine the 1st 2 Ebola-negative babies ever known to be born to Ebola-positive mothers. Both the mothers and babies received trial Ebola treatments while in an MSF-supported Ebola treatment center (ETC) in the Democratic Republic of Congo (DRC). Historically, nearly all babies born to Ebola-positive mothers have been miscarried or stillborn, or died shortly after birth.

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Thursday 10 December 2020

PRO/PL> Aphanomyces root rot, pea & lentil - Canada

Other Plant Disease -- Canada
Root disease is omnipresent in pulses in 2020. There were ideal conditions for aphanomyces in large parts of the prairies in the summer. But exactly how prevalent the disease was is largely unknown because researchers weren't allowed to do in-field surveys due to COVID-19. "So, I don't have hard numbers," said Agriculture Canada's Syama Chatterton.
Her informal survey was largely from pictures. "From what I gathered, it was a really rough year for aphanomyces," she said. Alberta Agriculture

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PRO/AH/EDR> COVID-19 update (531): animal, Canada (BC) mink, OIE

COVID-19 -- Canada
Information received on [and dated] 9 Dec 2020 from Dr Jaspinder Komal, Deputy Chief Veterinary Officer, Canadian Food Inspection Agency, Canadian Food Inspection Agency, Ottawa, Canada
Summary
Report type: immediate notification
Date of start of the event: 26 Nov 2020
Date of confirmation of the event: 8 Dec 2020
Reason for notification: emerging disease
Morbidity: 1%
Mortality: 1%
Zoonotic impact: zoonotic disease
Causal agent: SARS-CoV-2
New outbreaks (1)
Total outbreaks:

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PRO/AH/EDR> COVID-19 update (530): animal, mink, research, experimental infection, vaccine

COVID-19 -- China
Citation: Shuai L, Zhong G, Yuan Q, Wen Z, et al.: Replication, pathogenicity, and transmission of SARS-CoV-2 in minks. National Science Review. 2020; nwaa291, doi: (published 8 Dec 2020).
Abstract
Minks are raised in many countries and have transmitted severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper

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PRO/AH/EDR> COVID-19 update (529): indoor transmission risk, vaccines, surveillance, WHO, global

COVID-19 -- Worldwide/Unknown
WHO region (no. countries/territories):
Total confirmed cases (new cases in last 24 hours) / Total deaths (new deaths in last 24 hours)
----------------------------------------------------------------------
Western Pacific Region (19): 931 803 (5393) / 17 997 (151)
European Region (61): 20 869 839 (221 551) / 462 615 (5595)
South East Asia Region (10): 11 195 661 (43 803) / 170 284 (614)
Eastern Mediterranean Region (22): 4 256 386 (33 778) / 106 609 (696)
Eastern Mediterranean Region

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PRO/AH/EDR> Equine influenza - USA (07): (OR) horse

Equine Influenza -- United States
On 1 Dec 2020, an attending veterinarian confirmed a horse at a private facility in Clackamas County, Oregon, with equine influenza (EI). The 13-year-old Paint gelding, which was undervaccinated, began showing clinical signs on [26 Nov 2020]. Signs consisted of mild fever, nasal discharge, and mild cough. A voluntary quarantine has been enacted on his premises. No other horses were exposed.
Equine influenza is a highly contagious respiratory disease infecting horses, ponies, and other

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PRO/EDR> Undiagnosed illness - India (07): (AP) fatal, investigation continues

Undiagnosed -- India
A 9-member team of the National Institute of Nutrition (NIN), Hyderabad on Tuesday [8 Dec 2020] collected samples of water, milk, rice, vegetables, along with the blood and urine sample of patients after a massive number of people fell sick due to unknown disease in Eluru town of Andhra Pradesh.
"They have collected blood and urine samples of patients from hospitals. Later they went to places in town where the cases have been developed. The team collected samples of water, milk, rice, and

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Wednesday 9 December 2020

PRO/AH/EDR> Peste des petits ruminants - China: (QH) sheep

Peste des petits ruminants -- China
The Qinghai Animal Disease Control Center confirmed on 1 Dec 2020 an outbreak of peste des petits ruminants in Golmund city, Haixi prefecture, Qinghai province. A batch of 159 imported sheep was affected, of which 106 got sick and died. After the outbreak, the local authorities applied the epidemiological activities in accordance with relevant programs and technical specifications for prevention and control.
--
Communicated by:
ProMED-mail

[Peste des petits ruminants (PPR) is an acute

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PRO/AH/EDR> Avian influenza (106): Poland, Belgium, poultry, captive bird, HPAI H5N8, H5, OIE

Avian Influenza H5N8 -- Poland
Information received on [and dated] 8 Dec 2020 from Dr. Bogdan Konopka, Chief Veterinary Officer, Ministry of Agriculture and Rural Development, General Veterinary Inspectorate, Warsaw, Poland
Summary
Report type: Immediate notification
Date of start of the event: 3 Dec 2020
Date of confirmation of the event: 4 Dec 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: 13 May 2020
Manifestation of disease: Clinical disease
Causal agent: Highly

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PRO/AH/EDR> Australian bat lyssavirus - Australia: (QL) bat

Other Animal Disease -- Australia
A Biosecurity Queensland laboratory test has confirmed a case of lyssavirus in a bat found in the state's far north as health authorities report a surge in flying fox bites and scratches.
The ABC understands the little red flying fox was found in suburban Cairns and euthanised by a local wildlife carer who then sent the animal to Brisbane for testing.
Biosecurity Queensland principal veterinary officer Janine Barrett confirmed this was the 3rd infected bat discovered in 2020 following a

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PRO/AH/EDR> Anthrax - Croatia (02): (ZD) cattle conf, horse susp, OIE

Anthrax -- Croatia
Information received on [and dated] 8 Dec 2020 from Dr. Tatjana Karacic, Assistant Minister, Chief Veterinary Officer, Veterinary Services, Ministry of Agriculture, Zagreb, Croatia
Summary
Report type: Immediate notification
Date of start of the event: 4 Dec 2020
Date of confirmation of the event: 8 Dec 2020
Report date: 8 Dec 2020
Date submitted to OIE: 8 Dec 2020
Reason for notification: Recurrence of a listed disease
Date of previous occurrence: October 2007
Manifestation of

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PRO/AH/EDR> Anthrax - India (06): (AS) elephant, conf

Anthrax -- India
The carcass of a wild elephant found inside Joypur reserve forest in Assam's Dibrugarh district last week has tested positive for anthrax, the Wildlife Trust of India (WTI) said Wednesday [9 Dec 2020]. Though the highly infectious disease caused by the bacteria called _[Bacillus] anthracis_ had earlier been detected in cattle in the state, this is likely to be the 1st confirmed case of anthrax in wild elephants in Assam.
Forest officials had found the carcass of a sub-adult female aged

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PRO/ALL> New in IJID (12): December 2020

COVID-19, Zika virus, Influenza, E. coli, Tuberculosis, Norovirus, HIV/AIDS, Other Human Disease, Leishmaniasis, Malaria, Hepatitis, Histoplasmosis -- Worldwide/Unknown
Editorial
---------
Lessons from the COVID-19 pandemic -- unique opportunities for unifying, revamping and reshaping epidemic preparedness of Europe's public health systems
Giuseppe Ippolito, Francesco Nicola Lauria, Franco Locatelli, et al. IJID 2020; 101: 361-366.

Clinical
--------
COVID-19 and sickle cell disease in Bahrain
Abdulkarim Abdul Rahman, Salman AlAli, Omar Yaghi, et al. IJID 2020; 101:14-16.

SARS-CoV-2 infection does not induce HIV viral escape in the central

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PRO/AH/EDR> COVID-19 update (528): heterologous prime-boost, mass test, WHO, global

COVID-19 -- United Kingdom
1. Lu S. Heterologous prime-boost vaccination. Curr Opin Immunol. 2009; 21(3): 346-51. doi: 10.1016/j.coi.2009.05.016. Epub 2009 Jun 6; .
2. Hu SL, Abrams K, Barber GN, et al. Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science. 1992; 255: 456-459. doi: 10.1126/science.1531159; .
3. Agrawal B. Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections. Front Immunol. 2019; 10:2631. Published 2019 Nov 8; doi:

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PRO/AH/EDR> Avian influenza (105): China (SX) wild bird, HPAI H5N8, OIE

Avian Influenza H5N8 -- China
Information received on [and dated] 30 Nov 2020 from Dr Huang Baoxu, Secretary of the Party Leadership Group, Animal Health and Epidemiology Centre, Ministry of Agriculture and Rural Affairs, Qingdao, China (People's Rep. of)
Summary
Report type: immediate notification
Date of start of the event: 19 Nov 2020
Date of confirmation of the event: 26 Nov 2020
Reason for notification: new strain of a listed disease
Manifestation of disease: clinical disease
Causal agent: highly pathogenic

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PRO/EDR> Undiagnosed illness - India (06): (AP) fatal, organochlorine pesticide susp, RFI

Undiagnosed -- India
- Water samples sent for heavy metal analysis.
- 9 units of milk samples from the affected areas have been sent for testing.
- Rapid antigen test was done and reported negative for COVID-19
- Random sampling CSF samples were taken and reports are normal.
- Blood samples were taken for Hb, CBP [complete blood picture], LFT [liver function test], RFT [renal function test] and GRBS [random blood glucose test] -- all are normal.
- Blood samples were inoculated and reports are awaited.
-

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Tuesday 8 December 2020

PRO/EDR> Undiagnosed illness - India (05): (AD) fatal, RFI

Undiagnosed -- India
Special teams of doctors have been rushed to Eluru to treat the victims while a house-to-house survey has been undertaken to identify prospective patients.
Andhra Pradesh Chief Minister YS Jagan Mohan Reddy on Monday [7 Dec 2020] visited the Government General Hospital and interacted with those afflicted by the mysterious disease even as the number of patients rose.
Deputy Chief Minister (Health) AKK Srinivas (Nani), who represents Eluru, said tests established water contamination was

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PRO/AH/EDR> COVID-19 update (527): animal, Greece (WM) mink, spread, genome analysis

COVID-19 -- Greece
Following the 1st confirmed case, which was reported on 16 Nov 2020 [https://bit.ly/398uU4p], I would like to inform you about 11 further cases of SARS-Cov-2 detection on mink farms. They are located in the Region of Western Macedonia and in particular in the Regional Units of Kozani (5), Kastoria (4) and Grevena (2).
All new positive farms but one were inspected following notification of confirmed human cases in the framework of the repeated weekly surveillance that is

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PRO/AH/EDR> Anthrax - India (05): (AS) elephant

Anthrax -- India
The recovery of the bodies of a female elephant and a calf within 3 days in Joypur rainforest in Dibrugarh district has spread an anthrax scare in the forest area.
On 3 Dec 2020, inside the Joypur rainforest of Naharkatia, the body of an elephant calf was recovered. The veterinarians from Tinsukia Guijan and Naharkatia suspected the cause of death of the elephant calf to be infection of anthrax. The fear of anthrax thickened on 5 Dec 2020 after the recovery of the carcass of a female

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PRO/AH/EDR> COVID-19 update (526): Canada (BC) animal, mink, human

COVID-19 -- Canada
It is currently unclear what will happen to the mink at this farm or whether they even have the disease. The outlook could be grim. Farmers in the entire region, or even country, will likely be following the outbreak with trepidation given the swift and heavy handed responses authorities around the world have taken when there have been outbreaks at mink farms. Denmark, for instance, illegally ordered the cull of its entire 17 million-strong herd after discovering a potentially dangerous

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PRO/AH/EDR> COVID-19 update (525): Spain, animal, zoo, lion, human

COVID-19 -- Spain
Veterinary authorities said on Tuesday [8 Dec 2020] that 4 lions at Barcelona Zoo have tested positive for COVID-19, in only the 2nd known case in which large felines have contracted coronavirus.
Three females named Zala, Nima, and Run Run and Kiumbe, a male, were tested after keepers noticed they showed slight [clinical signs] of coronavirus.
The authorities said 2 staff at the zoo also tested positive for coronavirus, after the outbreak was first detected last month [November

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PRO/AH/EDR> COVID-19 update (524): import impact, vaccine distribution, Thailand, WHO, global

COVID-19 -- Brazil
Summary
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Background
Countries have restricted international arrivals to delay the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These measures carry a high economic and social cost, and might have little effect on COVID-19 epidemics if there are many more cases resulting from local transmission compared with imported cases. Our study aims to investigate the extent to which imported cases contribute to local transmission under different epidemic

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