Saturday, 15 July 2017

PRO/EDR> Meningococcal disease, eculizumab: complement deficiency, increased risk

Meningitis - Neisseria -- Worldwide/Unknown
McNamara LA, Topaz N, Wang X, Hariri S, Fox L, MacNeil JR
"Use of eculizumab (Soliris, Alexion Pharmaceuticals), a terminal complement inhibitor, is associated with a 1000-fold to 2000-fold increased incidence of meningococcal disease (1). Administration of meningococcal vaccines is recommended for patients receiving eculizumab before beginning treatment (2,3). Sixteen cases of meningococcal disease were identified in eculizumab recipients in the United States during 2008-2016; among these,

Read more about it at HealthMap Global Disease Alerts via http://bit.ly/2tdYe62

No comments:

Post a Comment