Norovirus -- Worldwide/Unknown
Noroviruses, the leading cause of severe gastroenteritis worldwide, have 6 genogroups and 38 genotypes; strain GII.4 is most frequently associated with outbreaks (NEJM JW Infect Dis Mar 2013 and MMWR Morb Mortal Wkly Rep 2013; 62:55).
Histo-blood group antigens (HBGAs) may act as attachment factors for norovirus: People with a functional FUT2 gene (secretors) express HBGAs on mucosal epithelium; nonsecretors, who have a FUT2 mutation of guanine-to-adenine at codon 428, are presumed to be
Read more about it at HealthMap Global Disease Alerts via http://bit.ly/1W1B1Id
No comments:
Post a Comment