Yellow Fever -- Uganda
Summary
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Background
Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine. We assessed the immunogenicity and safety of 1/5 fractional dose compared with standard dose of 4 WHO-prequalified yellow fever vaccines produced from 3 substrains.
Methods
We did this randomised, double-blind, non-inferiority trial at research centres in Mbarara,
Read more about it at HealthMap Global Disease Alerts via http://healthmap.org/ln.php?8136882&promed&0
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