Hepatitis E -- France
The case report of a severe infection with hepatitis E traced to a platelet transfusion is the kind of unusually severe infection which is the consequence of a hitherto unsuspected genetic immune defect. The high viral titers are consistent [with] such an event in this patient. With appropriate specimens and current methodologies, it is frequently possible to demonstrate such a mutation from the analysis of a single patient (1).
1. Casanova JL, Conley ME, Seligman SJ, Abel L, Notarangelo
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